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ChemInform Abstract: Biocatalytic Asymmetric Oxidation for the Production of Bicyclic Proline Peptidomimetics

✍ Scribed by James J. Lalonde; Jack Liang


Book ID
102067567
Publisher
John Wiley and Sons
Year
2011
Weight
18 KB
Volume
42
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A Sequential Electr
✍ L. M. BEAL; K. D. MOELLER πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 34 KB πŸ‘ 1 views

A Sequential Electrochemical Oxidation-Olefin Metathesis Strategy for the Construction of Bicyclic Lactam Based Peptidomimetics. -Anodic oxidation of the proline ester (I) and following addition of allylsilane provides 2 allylated prolines of which (III) is elaborated to the dienic compound (V). Its