✦ LIBER ✦
ChemInform Abstract: Benzothiazol-2-ylcarboxylic Acids with Diverse Spacers: A Novel Class of Potent, Orally Active Aldose Reductase Inhibitors.
✍ Scribed by T. AOTSUKA; N. ABE; K. FUKUSHIMA; N. ASHIZAWA; M. YOSHIDA
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 32 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Benzothiazol-2-ylcarboxylic Acids with Diverse Spacers: A Novel Class of Potent, Orally Active Aldose Reductase Inhibitors.
-Among the newly synthesized title compounds (III), (VI) (no yields given) various derivatives proved to be active as aldose reductase inhibitors. One of the most potent compounds (IIIb) with good oral absorption and low toxicity is evaluated for further investigations on the pharmacological profile.
-(AOTSUKA, T.;