𝔖 Bobbio Scriptorium
✦   LIBER   ✦

ChemInform Abstract: Benzimidazo(1,2-c)quinazoline Dimers as Potential Antitumor Agents.

✍ Scribed by M. F. BRANA; M. J. PEREZ DE VEGA; D. PERRON; D. CONLON; P. F. BOUSQUET; S. P. ROBINSON


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
28
Category
Article
ISSN
0931-7597

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Benzimidazo[1,2-c]quinazoline dimers as
✍ Miguel F. BraΓ±a; MarΓ­a JesΓΊs PΓ©rez de Vega; Denise Perron; Donna Conlon; Peter F πŸ“‚ Article πŸ“… 1997 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 451 KB πŸ‘ 1 views

## Abstract The 6‐substituted benzimidazo[1,2‐__c__]quinazoline 1 is a lead structure from our DNA intercalator program and is cytotoxic to the human colon cancer tumor line HT‐29 with an inhibitory concentration 50, IC~50~ of 4.00 ΞΌ__M__. In order to try and improve the limited cytotoxicity of thi