ChemInform Abstract: Base-Mediated Tandem Reaction Consisting of an Acyl Shift Strategy Leading to 4,5-Disubstituted Furan-2(5H)-ones.

Base-Mediated Tandem Reaction Consisting

Base-Mediated Tandem Reaction Consisting of an Acyl Shift Strategy Leading to 4,5-Disubstiuted Furan-2(5H)-ones

✍ Yong Lei; Zhi-Qiang Wang; Ye-Xiang Xie; Shang-Ci Yu; Bo-Xiao Tang; Jin-Heng Li 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 197 KB 👁 1 views

## Abstract The first example of the synthesis of 4,5‐disubstiuted furan‐2(5__H__)‐ones by base‐mediated tandem acyl shift/cyclization/decarbonylation reactions of aroylmethyl 2‐alkynoates has been developed. This new and inexpensive tandem route allows both a CO bond and a C__sp__^__3__^C__sp__^