ChemInform Abstract: Azabicyclo[3.2.0]heptan-7-ones (Carbapenams) from Pyrrole.

✍ Scribed by T. L. GILCHRIST; A. LEMOS; C. J. OTTAWAY

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 36 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199807261

✦ Synopsis

Azabicyclo[3.2.0]heptan-7-ones (Carbapenams) from Pyrrole.

-An approach to carbapenam derivatives such as (XII) and (XIV) is developed which is quite flexible in terms of types of substituents that can be incorporated into the desired product. In some cases such as (IX) a high degree of stereoselectivity is observed in the hydrogenation step. The relative stereochemistry of (XI) is determined by X-ray analysis. -(GILCHRIST, T.