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ChemInform Abstract: Attempted Synthesis of a Tenidap Isomer and Formation of an Unexpected Stable Water Adduct.

✍ Scribed by Klara Esses-Reiter; Jozsef Reiter

Publisher
John Wiley and Sons
Year
2001
Weight
29 KB
Volume
32
Category
Article
ISSN
0931-7597

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Attempted synthesis of a tenidap isomer
Attempted synthesis of a tenidap isomer and formation of an unexpected stable water adduct
✍ KlΓ‘ra Esses-Reiter; JΓ³zsef Reiter πŸ“‚ Article πŸ“… 2000 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 478 KB

## Abstract An attempt to synthesize the Tenidap isomer **13** was performed starting from 2‐ethoxy‐5‐chloroindole (**9**). The acylation and carbamoylation reactions of **9** led to the expected intermediate **12**, however the hydrolysis of **12** in acidic or alkaline media did not yielded the e