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ChemInform Abstract: Asymmetric Synthesis of the Sulfoxide Metabolite of ON-579 by the Kagan Protocol.

✍ Scribed by M. SATO; A. MANAKA; Y. KAWASHIMA; K. TOMISAWA; C. IWATA


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Direct Synthesis of
✍ D. CRICH; S. SUN πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 31 KB πŸ‘ 1 views

Direct Synthesis of Ξ²-Mannopyranosides by the Sulfoxide Method. -The activation of a glycosyl donor via the sulfoxide group followed by addition of a glycosyl acceptor in CH2Cl2 results in the formation of mannopyranosides in high yield and high Ξ²:Ξ±-ratios. Reducing the bulk of the O-2 protecting g