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ChemInform Abstract: Asymmetric Synthesis of (R)-Nilvadipine and (S)-NB 818 via Regioselective Bromination of Chiral 1,4-Dihydropyridines as a Key Step and Enzymatic Resolution of Racemic 2-Hydroxymethyl-1,4- dihydropyridine Derivatives.

โœ Scribed by H. EBIIKE; K. MARUYAMA; Y. OZAWA; Y. YAMAZAKI; K. ACHIWA

Publisher
John Wiley and Sons
Year
2010
Weight
37 KB
Volume
28
Category
Article
ISSN
0931-7597

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## Abstract The process offers a convenient access to the desired heterocyclic skeleton, present in alkaloids and synthetic drugs.