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ChemInform Abstract: Asymmetric Synthesis of (R)(-)-Dimethyl Citramalate.

✍ Scribed by S. JEW; H. KIM; S. SONG; J. JANG; H. PARK

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Asymmetric Synthesis of (R)(-)-Dimethyl Citramalate.

-The asymmetric synthesis of the title compound (IX), chiral building block in natural product synthesis, involves the iodolactonization of (IV) using (S)-(-)-proline as a chiral auxiliary in the key step.

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