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ChemInform Abstract: Asymmetric Synthesis of Chiral Fluorinated Compounds Using N- Acyloxazolidinones

โœ Scribed by K. ISEKI; Y. KOBAYASHI


Book ID
112036150
Publisher
John Wiley and Sons
Year
2010
Weight
24 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Synthesi
โœ W. OPPOLZER; O. FROELICH; C. WIAUX-ZAMAR; G. BERNARDINELLI ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 33 KB ๐Ÿ‘ 2 views

The diastereomerically pure sulfinylating reagent (III) reacts with nucleophilic Grignard reagents or the zinc reagent derived from (VI) to yield chiral sulfoxides with excellent yields and enantioselectivities. Under specific conditions sequential reaction of (III) with LiN(Tms)2 followed by aldehy