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ChemInform Abstract: Asymmetric Synthesis of Bryostatin 2.

✍ Scribed by D. A. EVANS; P. H. CARTER; E. M. CARREIRA; J. A. PRUNET; A. B. CHARETTE; M. LAUTENS

Publisher: John Wiley and Sons
Year: 2010
Weight: 25 KB
Volume: 30
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199903234

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✦ Synopsis

Asymmetric Synthesis of Bryostatin 2.

-The title compound (Ia), which can be converted in 3 steps into the biologically active marine macrolide bryostatin 1 (Ib), is totally synthesized by coupling of 3 acyclic fragments.

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