ChemInform Abstract: Asymmetric Synthesis of Boc-β2-homophenylglycine.
✍ Scribed by R. PONSINET; G. CHASSAING; S. LAVIELLE
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 33 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0931-7597
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✦ Synopsis
Asymmetric Synthesis of Boc-β 2 -homophenylglycine.
-Key step in the synthesis of the title compound, which is presented with a view to the current interest in non-proteinogenic amino acids, is the diastereoselective acylation of phenylacetonitrile with sultam carbonyl chloride (II), prepared from Oppolzer's sultam and triphosgene.
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