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ChemInform Abstract: Asymmetric Synthesis of 4-Phenyl-1,5-diazacyclooctan-2-one Using Optically Active Vinyl Sulfoxides.

โœ Scribed by N. ITOH; H. MATSUYAMA; M. YOSHIDA; N. KAMIGATA; M. IYODA


Book ID
112029072
Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
27
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Optically Active 2,
โœ Remir G. Kostyanovsky; Pavel E. Dormov; Peteris Trapencieris; Boriss Strumfs; Gu ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 31 KB ๐Ÿ‘ 1 views

The racemic title bicycle (V) undergoes spontaneous resolution on crystallization from chloroform or acetone. The absolute configuration of the obtained enantiopure product (16-44% e.e.) is determined by comparison with (S)-(V) derived from (S)-Ser-OMe (I). Mutarotation due to partial conversion of