ChemInform Abstract: Asymmetric Synthesis of 2,3-Dihydro-4-pyranones by Reaction of Chiral 3-Alkoxycyclobutanone and Aldehydes.

✍ Scribed by Shoko Negishi; Hiroyuki Ishibashi; Jun-ichi Matsuo

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 30 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201109143

✦ Synopsis

Asymmetric Synthesis of 2,3-Dihydro-4-pyranones by Reaction of Chiral 3-Alkoxycyclobutanone and Aldehydes. -The cyclobutanone (I) bearing L-ethyl lactate as chiral auxiliary is found to be highly suitable for the preparation of the pyran derivatives with good to excellent e.e. values. -(NEGISHI, S.; ISHIBASHI, H.;