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ChemInform Abstract: Asymmetric Synthesis and Enantioselectivity of Binding of 1-Aryl-1,2,3,4-tetrahydroisoquinolines at the PCP Site of the NMDA Receptor Complex.

✍ Scribed by K. TH. WANNER; H. BEER; G. HOEFNER; M. LUDWIG


Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
30
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.


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A new method for the asymmetric synthesis of 1-substituted enantiomerically pure 11c-g and 12c-g (ee ΟΎ 99 %), 1-aryltetrahydroisoquinolines, were evaluated for their affinity to tetrahydroisoquinolines is presented. It is based on stereoselective addition reactions of organometallic the PCP [1-(1-ph

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v