ChemInform Abstract: Asymmetric Routes Towards Polyfunctionalized Pyrrolidines: Synthesis and Reactivity of a Chiral Silyloxypyrrole.
β Scribed by I. BAUSSANNE; J. ROYER
- Book ID
- 112033693
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0931-7597
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π SIMILAR VOLUMES
Starting from the (R)-(-)-phenylglycinol derivative (I), the stereoselective synthesis of polyhydroxylated pyrrolidines [cf. (VIII)] and the indolizidine (XII) is based on the diastereoselective condensation of the chiral silyloxypyrrole (III) with aldehydes (IV). The preparation of the indolizidine
Asymmetric Synthesis of 2,4-Disubstituted Pyrrolidines. -Starting with the chiral synthon (I), the 2,4-disubstituted pyrrolidines (VI) and (VIII) are synthesized enantiospecifically via the common intermediate (III). -(WANG, Q.;
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