✦ LIBER ✦
ChemInform Abstract: Asymmetric Reduction of Ketoxime Ethers to Optically Active O- Substituted Hydroxylamines with Reagents Prepared from Borane and Chiral Amino Alcohols.
✍ Scribed by J. T. DOUGHERTY; J. R. FLILSAK; J. HAYES; I. LANTOS; L. LIU; L. TUCKER
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 29 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
✦ Synopsis
Asymmetric Reduction of Ketoxime Ethers to Optically Active O-Substituted Hydroxylamines with Reagents Prepared from Borane and Chiral Amino Alcohols.
-The reduction in the presence of norephedrine is an efficient method to prepare chiral O-substituted hydroxylamines. However, O-Tbs and O-tBu substituted oximes are not reduced and O-methoxymethyl, O-(2-methoxyethoxymethyl), and O-allyl substituted oximes lead to complicated reaction mixtures.
-(DOUGHERTY, J. T.;