ChemInform Abstract: Asymmetric Phase-Transfer Alkylation Catalyzed by a Chiral Quaternary Phosphonium Salt with a Multiple Hydrogen-Bonding Site.

✍ Scribed by K. MANABE

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 29 KB
• Volume: 29
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199844040

✦ Synopsis

Asymmetric Phase-Transfer Alkylation Catalyzed by a Chiral Quaternary Phosphonium Salt with a Multiple Hydrogen-Bonding Site.

-The chiral phosphonium salt (II) is synthesized and used as a phase-transfer catalyst in the asymmetric benzylation of (III). Under the same conditions, a phosphonium salt with only one mandelamide unit affords the benzylated product (V) in almost racemic form. -(MANABE, K.;