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ChemInform Abstract: Asymmetric Hydrogenation of α-Primary and Secondary Amino Ketones: Efficient Asymmetric Syntheses of (-)-Arbutamine and (-)-Denopamine.

✍ Scribed by Gao Shang; Duan Liu; Scott E. Allen; Qin Yang; Xumu Zhang

Book ID
102010754
Publisher
John Wiley and Sons
Year
2008
Weight
65 KB
Volume
39
Category
Article
ISSN
0931-7597

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## Abstract Two β‐receptor agonists (−)‐denopamine and (−)‐arbutamine were prepared in good yields and enantioselectivities by asymmetric hydrogenation of unprotected amino ketones for the first time by using Rh catalysts bearing electron‐donating phosphine ligands. A series of α‐primary and second

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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v