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ChemInform Abstract: Asymmetric Dihydroxylation of Stachysterone C: Stereoselective Synthesis of 24-epi-Abutasterone.

โœ Scribed by B. YINGYONGNARONGKUL; A. SUKSAMRARN


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
29
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Asymmetric Synthesi
โœ M. NOWAKOWSKI; H. M. R. HOFFMANN ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 30 KB ๐Ÿ‘ 1 views

Asymmetric Synthesis of the C(18)-C(24) Unit of Lasonolide A. -The synthesis of the title compound (VIII) proceeds with high chiral efficiency. In six steps, four chiral centers are assembled. A key step is the modified Simpkins-Koga asym. deprotonation of compound (I). The strategy outlined is vers