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ChemInform Abstract: Asymmetric Broensted Acid-Catalyzed Friedel—Crafts Reactions of Indoles with Cyclic Imines — Efficient Generation of Nitrogen-Substituted Quaternary Carbon Centers.

✍ Scribed by Magnus Rueping; Sadiya Raja; Alberto Nunez


Publisher
John Wiley and Sons
Year
2011
Weight
33 KB
Volume
42
Category
Article
ISSN
0931-7597

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Asymmetric Brønsted Acid-Catalyzed Fried
✍ Magnus Rueping; Sadiya Raja; Alberto Núñez 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB 👁 1 views

## Abstract A new enantioselective Brønsted acid‐catalyzed Friedel–Crafts reaction of indole with cyclic imines has been develeoped. This organocatalytic reaction provides for the first time optically active indolindolinone derivatives in high yields and with excellent enantioselectivities (up to 9