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ChemInform Abstract: Approaches to Oximidines, Lobatamides and Related Natural Products: The Coupling Reactions of 3-Iodoacrolein O-Methyl Oximes.

โœ Scribed by Steven A. Raw; Richard J. K. Taylor


Book ID
101914622
Publisher
John Wiley and Sons
Year
2001
Weight
34 KB
Volume
32
Category
Article
ISSN
0931-7597

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Approaches to oximidines, lobatamides an
โœ Steven A Raw; Richard J.K Taylor ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 94 KB

Both 2E-and 2Z-3-iodoacrolein O-methyl oximes are prepared in two steps from ethyl propiolate. Lithium-iodine exchange is effected and the resulting organolithium reagents added to several electrophiles, including styryl isocyanate which gives a conjugated O-methyl oxime enamide of the type found in