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ChemInform Abstract: Antitumor Polycyclic Acridines. Part 5. Synthesis of 7H-Pyrido[4,3,2-kl]acridines with Exploitable Functionality in the Pyridine Ring.

✍ Scribed by M. JULINO; M. F. G. STEVENS

Publisher
John Wiley and Sons
Year
2010
Weight
40 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis

Antitumor Polycyclic Acridines. Part 5. Synthesis of 3,2kl]acridines with Exploitable Functionality in the Pyridine Ring. -In continuation of the program concerning the development of a new anticancer polycyclic acridine, a novel route to such compounds is presented. The advantage is the formation of a single triazolylacridine. A further cyclization to (X) is achieved if R 2 is a corresponding chlorobutyl side chain. -(JULINO, M.;

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