ChemInform Abstract: Antiinflammatories: Synthesis of a Nonsteroidal Antiinflammatory ML 3000
β Scribed by Janine Cossy
- Publisher
- John Wiley and Sons
- Year
- 2001
- Weight
- 23 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Compounds containing both the structural features of mesoionic sydnones and styrylketone (III) (9 examples) are designed and synthesized as potential analgesic and antiinflammatory agents using a ClaisenβSchmidt reaction.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Synthesis and Antiinflammatory Activity of Chalcone Derivatives. -Among the chalcones synthesized compounds (Ia)-(Ic) inhibit degranulation and 5-lipoxygenase in human neutrophils, (Id) inhibits cyclooxygenase-2 and (Ie) serves as scavenger of superoxide. -(HERENCIA, F.; FERRANDIZ,