Antibiotic resistance versus small molec
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Ving J. Lee; Scott J. Hecker
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Article
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1999
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John Wiley and Sons
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English
โ 402 KB
๐ 1 views
Two discovery approaches directed to addressing the problem of increasing bacterial resistance are described. The first is a program to build activity against methicillin-resistant Staphylococcus aureus (MRSA) into the cephalosporin class of antibacterials, by enhancing affinity for PBP2a, the penic