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ChemInform Abstract: Anomalous Fluorinations of 3-Aryl-2-hydroxypropanoic Esters by Diethylaminosulfur Trifluoride (DAST).

✍ Scribed by D. HAIGH; L. J. JEFCOTT; K. MAGEE; H. MCNAB


Publisher
John Wiley and Sons
Year
2010
Weight
30 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Diastereoselective
✍ Florence Roger; Marie-Gabrielle Le Pironnec; Michel Guerro; Patrick Gougeon; Phi πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 38 KB πŸ‘ 1 views

Diastereoselective Synthesis of N-(Ξ±-Aryl-Ξ±-haloacetyl) Amino Acid Esters by Acylation Using 3-Aryl-2,2-dicyanooxiranes. -Ξ±-ArylΞ±-bromo ketenes are generated in situ starting from epoxides (I) by treatment with Li 2 NiBr 4 , followed by the addition of Et 3 N at -78 β€’ C. Trapping of these intermedi