A Sequential Electrochemical Oxidation-Olefin Metathesis Strategy for the Construction of Bicyclic Lactam Based Peptidomimetics. -Anodic oxidation of the proline ester (I) and following addition of allylsilane provides 2 allylated prolines of which (III) is elaborated to the dienic compound (V). Its
ChemInform Abstract: An Olefin Metathesis Based Strategy for the Construction of the JKL, OPQ, and UVW Ring Systems of Maitotoxin.
β Scribed by K. C. NICOLAOU; M. H. D. POSTEMA; E. W. YUE; A. NADIN
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 34 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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An Expedient Route for the Stereoselective Construction of Bridged Polyheterocyclic Ring Systems Using the Tandem "Pincer" Diels-Alder Reaction. -The tandem Diels-Alder reaction of furans with acetylenes is found to proceed regio-and stereoselectively as well as chemoselectively. Reactions using th