Efficient Preparation of Substituted 5,6,7,8-Tetrahydroquinolines and Octahydroacridine Derivatives. -Enamine (II) reacts with ฮฒ-amine ketone hydrochloride (I) to afford the diketones (III) in moderate to good yields. The final cyclization to tetrahydroquinolines (IV) is achieved by refluxing (III)
โฆ LIBER โฆ
ChemInform Abstract: An N-Substituted 6,7-Benzocoumarin-8,9-aziridine Derivative.
โ Scribed by K. CHINNAKALI; H.-K. FUN; K. SRIRAGHAVAN; V. T. RAMAKRISHNAN; I. A. RAZAK
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 26 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0931-7597
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โฆ Synopsis
An N-Substituted 6,7-Benzocoumarin-8,9-aziridine Derivative.
-In the newly synthesized title compound (I), the tetrahydrobenzene ring adopts a flattened-boat conformation. In the crystal, the carbonyl O atom is involved in weak intermolecular hydrogen bonds. -(CHINNAKALI, K.;
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## Abstract Coumarin analogues bearing an acyl function at position 3, halogens at position 6, substituted or unsubstituted benzyloxy moieties at position 7, and a methyl group at position 8, are synthesized.
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