ChemInform Abstract: An Expeditious Approach to 1-(Isoquinolin-1-yl)guanidines via a Three-Component Reaction of 2-Alkynylbenzaldehyde, Sulfonohydrazide, with Carbodiimide.

✍ Scribed by Huanhuan Wang; Shengqing Ye; Hanpeng Jin; Jianping Liu; Jie Wu

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 28 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201149143

✦ Synopsis

Abstract

Among the novel isoquinolinylguanidines (IV), (VI) prepared, compounds with promising PTP1B inhibiting activity are identified.