ChemInform Abstract: An Enantioselective Entry to Linear, C2-Symmetrical and Pseudosymmetrical 1,6-Diamino-2,5-diols.

✍ Scribed by Nuria Aguilar; Albert Moyano; Miquel A. Pericas; Antoni Riera

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 35 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199935080

✦ Synopsis

An Enantioselective Entry to Linear, C 2 -Symmetrical and Pseudosymmetrical 1,6-Diamino-2,5-diols.

-Starting with the C 2symmetrical sulfur-tethered bis (amino alcohols) (I), which are prepared as described in the preceding paper, symmetrical 1,6-diamino-2,5-diols (VIII) are synthesized as outlined in the reaction scheme. The key step in this sequence, which is also applied to the synthesis of the pseudosymmetrical diamino-diol (IX), is the Ramberg-Baecklund reaction of (V). -(AGUILAR, NURIA;