ChemInform Abstract: An Efficient Synthesis of Highly Functionalized Chiral Lactams.

✍ Scribed by Martha A. Ornelas; Javier Gonzalez; Neal W. Sach; Paul F. Richardson; Kevin D. Bunker; Angelica Linton; Susan E. Kephart; Mason Pairish; Chuangxing Guo

• Publisher: John Wiley and Sons
• Year: 2011
• Weight: 33 KB
• Volume: 42
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.201149111

✦ Synopsis

Abstract

The S~N~Ar‐reaction of N‐benzylpantolactam (I) with various halides is shown to proceed with no or low amounts of racemization and can be used in library synthesis.