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ChemInform Abstract: An Efficient Copper-Free Pd(OAc)2/Ruphos-Catalyzed Sonogashira Coupling of 1-Chloroisoquinolines in the Formation of 1-Alkynyl-3-substituted Isoquinolines.

✍ Scribed by K. Prabakaran; F. Nawaz Khan; Jong Sung Jin


Publisher
John Wiley and Sons
Year
2011
Weight
26 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

The method avoids an oxidative dimerization of the alkynes and renders possible the simple access to biologically interesting isoquinoline structures.