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ChemInform Abstract: An Effective Procedure for the Synthesis of 1α,25- Dihydroxycholecalciferol (Calcitriol) Starting with 1α,3β, 25-Trihydroxycholesta-5,7-diene (Pro-Calcitriol).

✍ Scribed by M. REICHENBAECHER; S. GLIESING; C. LANGE; M. GONSCHIOR; B. SCHOENECKER


Book ID
101846344
Publisher
John Wiley and Sons
Year
2010
Weight
33 KB
Volume
28
Category
Article
ISSN
0931-7597

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✦ Synopsis


An Effective Procedure for the Synthesis of 1α,25-Dihydroxycholecalciferol (Calcitriol) Starting with 1α,3β, 25-Trihydroxycholesta-5,7diene (Pro-Calcitriol). -An effective synthesis of the important vitamin D metabolite calcitriol (III) via double wavelength irradiation of pro-calcitriol ( I) and thermal isomerization of the obtained photoisomer (II) is given.