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ChemInform Abstract: An Approach to the Skeleton of the Securinega Alkaloids. The Total Synthesis of (.+-.)-Securinine.

✍ Scribed by Spiros Liras; Jennifer E. Davoren; Jon Bordner


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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The securinega alkaloids are a family of approximately 20 tetracyclic compounds produced by several Securinega and Phyllanthus species of the Euphorbiaceae plant family. The major securinega alkaloid is securinine (1), isolated from the leaves of Securinega suffruticosa. Its enantiomer, virosecurin