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ChemInform Abstract: Aminocarbonyl Arylvinylbenzamides as Gastric Sparing Antiinflammatory Agents.

✍ Scribed by Saurabh C. Khadse; Gokul S. Talele; Surendra S. Agrawal


Publisher
John Wiley and Sons
Year
2011
Weight
26 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

A variety of the title arylvinylbenzamides (III) (15 examples) is synthesized by nucleophilic ring opening of corresponding azlactones with amines.


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## Abstract Following a Claisenβ€”Schmidt condensation between piperidine hydrochloride monohydrate (I) and aryl aldehydes (II) or an aldol condensation between (I) and aryl aldehydes (VI) gives rise to formation of curcumin analogues (III) and (VII).