Alkylation Studies with Isopropylidene M
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A. R. Kore; R. B. Mane; M. M. Salunkhe
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Article
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2010
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Wiley (John Wiley & Sons)
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lsopropylidene malonate (2,2-dimethyl-4,6-dioxo-l,3-dioxane, Meldrum's acid) has a high acidity (pK1 = 4.97), a rigid cyclic structure and can undergo easy hydrolysis. It has become an attractive reagent in or anic synthesis.' For example, it can readily undergo Knoevena el conden~ation?'~ Michael a