ChemInform Abstract: Addition of Isocyanides to α-(Methylthio)benzylidenamidinium Iodides: A Surprising Access to 2-(Dialkylamino)imidazoles and 3,5-Diamino-2H-pyrrolium Salts.

Addition of isocyanides to α-(methylthio

Addition of isocyanides to α-(methylthio)-benzylidenamidinium iodides: A surprising access to 2-(dialkylamino)imidazoles and 3,5-diamino-2H-pyrrolium salts

✍ Georges Morel; Evelyne Marchand; Yvelise Malvaut 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 186 KB

A number of 2-(dialkylamino)-5-(methylthio)imidazoles 2 are obtained by treating the formamidinium iodides 1a,b with isocyanides R 3 NC under mild conditions. Reduction of these species can occur in the reaction medium to furnish the corresponding imidazoles 3. In some cases, double cycloaddition ac