ChemInform Abstract: A β-Lactone Route to Chiral γ-Substituted α-Amino Acids: Application to the Concise Synthesis of (S)-α-Azidobutyro Lactone and a Natural Amino Acid.
✍ Scribed by Reginald L. Tennyson; Guillermo S. Cortez; Hector J. Galicia; Charles R. Kreiman; Christina M. Thompson; Daniel Romo
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 35 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0931-7597
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γ-Oxo-α,β-unsaturated δ-lactones and lactams, which are in high yields, of the corresponding α-amino-γ-oxo-α,βunsaturated δ-lactones and -lactams, compounds of great easily accessible from their corresponding 2-furylcarbinols, were used as substrates for the 1,4-reductive addition of biological and
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