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ChemInform Abstract: A Three-Component Domino Protocol for the Facile Synthesis of Highly Functionalized Tetrahydroisoquinolines by Creation of Their Benzene Ring.

✍ Scribed by Kamaraj Balamurugan; Veerappan Jeyachandran; Subbu Perumal; J. Carlos Menendez

Publisher
John Wiley and Sons
Year
2011
Weight
53 KB
Volume
42
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

The one‐pot three‐component protocol for the synthesis of polysubstituted tetrahydroisoquinolines proceeds via a domino Knoevenagel condensation/ Michael addition/ Thorpeβ€”Ziegler cyclization/ air promoted dehydrogenation sequence.

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