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ChemInform Abstract: A Synthetic Approach to (.+-.)-Forskolin. Part 1. Preparation of Key Hydrobenzofuran Intermediates.

✍ Scribed by C. ANIES; A. PANCRAZI; J.-Y. LALLEMAND


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
28
Category
Article
ISSN
0931-7597

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ChemInform Abstract: A New Synthetic App
✍ I. HANNA; P. WLODYKA πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 2 views

The functionalized tricyclic framework (XI) of the diterpene forskolin is synthesized by an intramolecular Diels-Alder reaction of the dienyne (VII), which is obtained by stereoselective introduction of the C side chains at C-1 and C-2 of tri-O-acetyl-D-galactal (I) via C-Ferrier and Claisen-Ireland