ChemInform Abstract: A Straightforward Synthetic Approach for Roxindole.

✍ Scribed by Jos H. M. Lange; Johannes C. de Jong; Hans J. Sanders; Geb M. Visser; Chris G. Kruse

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 28 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199932106

✦ Synopsis

simple synthesis of roxindole (VI) starting from cheap materials and including key-step formation of acid (III) by reaction of Grignard intermediate and succinic anhydride is described. -(