ChemInform Abstract: A Simple Synthesis of New Carbinols from Bis(2-benzothiazolyl) Ketone.
β Scribed by C. BOGA; L. FORLANI; P. E. TODESCO
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 28 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
A Simple Synthesis of New Carbinols from Bis(2-benzothiazolyl) Ketone.
-The addition of Grignard reagents to the title compund (II) affords the corresponding carbinols (IV) under mild conditions in excellent yields without any side products. Even bulky nucleophiles give almost quantitative yields.
π SIMILAR VOLUMES
Unexpected Regioselectivity in the Attack of Vinyl Grignard Reagents to Bis(2-benzothiazolyl) Ketone. -Surprisingly, the reaction of ketone (I) with vinylmagnesium bromide ( IIa) does not give the expected carbinol (IVa) by normal 1,2-carbonyl addition but the vinyl ether (IIIa) is obtained exclusiv
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