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ChemInform Abstract: A Simple Synthesis of 8-(Methoxycarbonyl)octyl 3,6-Di-O-(α-D-mannopyranosyl)-α-D-mannopyranoside and Derivatives and Their Use in the Preparation of Neoglycoconjugates.

✍ Scribed by Bernd Becker; Richard H. Furneaux; Folkert Reck; Oleg A. Zubkov


Publisher
John Wiley and Sons
Year
2010
Weight
28 KB
Volume
30
Category
Article
ISSN
0931-7597

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The preparation of a beta-galactosylated hydroxyproline derivative and its use in the multi-gram solid-phase synthesis of the potent analgesic neoglycopeptide O1.5-beta-D-galactopyranosyl [D-Met2, Hyp5]enkephalinamide is described in this paper. The most closely related impurities have been identifi