ChemInform Abstract: A Simple and Efficient Method of Preparing α-Bromocarboxylic Acids.

✍ Scribed by Lian Hao Zhang; Jianxin Duan; Yuelian Xu; William R. Jr. Dolbier

• Publisher: John Wiley and Sons
• Year: 2010
• Weight: 31 KB
• Volume: 30
• Category: Article
• ISSN: 0931-7597
• DOI: 10.1002/chin.199910077

✦ Synopsis

1999 halogenated carboxylic acids and esters halogenated carboxylic acids and esters (acyclic compounds) P 0260 10 -077 A Simple and Efficient Method of Preparing α-Bromocarboxylic Acids.

-The novel reagent NBS/TFA/H 2 SO 4 is investigated for the bromination of carboxylic acids (I). It allows the high-yielding synthesis of αbromocarboxylic acids without formation of dibromo compounds. -(ZHANG,