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ChemInform Abstract: A Short Synthesis of Argatroban: A Potent Selective Thrombin Inhibitor.

✍ Scribed by Janine Cossy; Damien Belotti

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
32
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable via the β€œReferences” option.

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Synthesis, Evaluation, and Crystallographic Analysis of L-371,912: A Potent and Selective Active-Site Thrombin Inhibitor. -Two major synthetic challenges are apparent in more efficient approaches to the synthesis of the novel trans 4-aminocyclohexylglycine ketoamide found in inhibitor (IX). The firs