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ChemInform Abstract: A Short Path Synthesis of α-Hydroxy Ester from Aldehyde Using (1-Ethoxyvinyl)lithium and Its Application to the Syntheses of Thymine Polyoxin C and Uracil Polyoxin C.

✍ Scribed by H. AKITA; K. UCHIDA; C. Y. CHEN


Publisher
John Wiley and Sons
Year
2010
Weight
35 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


Ester from Aldehyde Using (1-Ethoxyvinyl)lithium and Its Application to the Syntheses of Thymine Polyoxin C and Uracil Polyoxin C.

-Starting from the known aldehyde (I), derived from D-ribose, a short synthesis to the key synthon (IV) is presented. The latter is subsequently converted to the title compounds (VIII) via coupling products (VII). -(AKITA, H.;