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ChemInform Abstract: A Remarkable Stereocontrol During Cobalt(II) Chloride Catalyzed Opening of Cinnamoyl Epoxides with N-Substituted Anilines.

✍ Scribed by A. DE; S. GHOSH; J. IQBAL


Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
29
Category
Article
ISSN
0931-7597

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✦ Synopsis


A Remarkable Stereocontrol During Cobalt(II) Chloride Catalyzed Opening of Cinnamoyl Epoxides with N-Substituted Anilines.

-The stereochemistry of the ring cleavage is controlled by the para-substituent of the aromatic ring directly attached to the nitrogen of the aniline. para-Methoxy groups cause formation of anti amino alcohols; amines with para-Cl, -Br, -Me, or hydrogen substituents afford syn products. -(DE, A.