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ChemInform Abstract: A Regio- and Stereoselective 1,3-Dipolar Cycloaddition for the Synthesis of Novel Spiro-Pyrrolothiazolyloxindoles and Their Antitubercular Evaluation.

✍ Scribed by Pitchaimani Prasanna; Kamaraj Balamurugan; Subbu Perumal; Perumal Yogeewari; Dharmarajan Sriram

Publisher: John Wiley and Sons
Year: 2011
Weight: 26 KB
Volume: 42
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201114145

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✦ Synopsis

Abstract

Cycloaddition of azomethine ylides, generated in situ via decarboxylative condensation of isatins (II) and thiazolanecarboxylic acid (III) to indenones (I) provides the novel spiro compounds (IV).

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