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ChemInform Abstract: A Novel Synthesis of Pyrrolo[1,2-d][1,4]diazocines from Tetrahydropyrrolo[1,2-a]pyrazines Using Activated Alkynes in Pyrazine Ring Expansion.

โœ Scribed by Leonid G. Voskressensky; Alexander A. Titov; Tatiana N. Borisova; Anna V. Listratova; Roman S. Borisov; Larisa N. Kulikova; Alexey V. Varlamov


Publisher
John Wiley and Sons
Year
2010
Weight
36 KB
Volume
41
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Synthesis of Pyrrol
โœ Maloy Nayak; Garima Pandey; Sanjay Batra ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› John Wiley and Sons โš– 43 KB

## Abstract Key feature of the synthesis of title pyrrolopyrazine scaffolds is the Curtius reaction of formylpyrrolylโ€substituted acids to generate an isocyanate, which is directly cyclized in the presence of formic acid [cf.