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ChemInform Abstract: A Novel Synthesis of Pyrazolo(1,2-b)phthalazines and Pyrido(2′,3′:3,4) pyrazolo(1,2-b)phthalazines; a New Ring System.

✍ Scribed by A. Z. A. A. ELASSAR; Y. M. ELKHOLY; M. H. ELNAGDI

Publisher: John Wiley and Sons
Year: 2010
Weight: 31 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199706148

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✦ Synopsis

A Novel Synthesis of Pyrazolo(1,2-b)phthalazines and Pyrido(2',3':3,4) pyrazolo(1,2-b)phthalazines; a New Ring System. -Base-catalyzed reaction of phthalhydrazide (I) with malonic acid derivatives provides smoothly pyrazolophthalazines (cf. (III), (X)) which can be transformed into novel pyridopyrazolophthalazines (cf. ( IX)) by reaction with ylidenemalononitriles. -(ELASSAR, A.

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